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Pfizer says it is not known if Covid-19 protection holds up after a single dose of vaccine



Pfizer Inc. has said the second dose of its Covid-19 vaccine should be given to individuals within the recommended 21-day timeframe, questioning a UK decision to space out the dosing schedule. The UK’s decision not to withhold any part of its vaccine supply aims to quickly reach as many high-risk people as possible. As part of the government plan, the second could be given up to 12 weeks later, longer than the three-week timeframe determined to be optimal by Pfizer’s cutting-edge studies and the four weeks suggested for the vaccine developed by Moderna. Inc. People should get them on the recommended schedule, Pfizer said Thursday, warning that “there is no data to show that protection after the first dose is maintained after 21 days.” Information about the effectiveness of a single dose has been misinterpreted, said Peter Marks, director of the U.S. Food and Drug Administration office that oversees vaccines. Relying on one shot, he said, “is worrying.” “If people don’t really know how protective a vaccine is,” Marks said in an email, “there’s a risk of harm because they can assume they’re fully protected when they don’t. are not and change their behavior to take unnecessary risks. Marks’ comments come as the British Medical Association said on Thursday that the UK’s decision would force doctors to postpone the appointments of tens of thousands of elderly and vulnerable patients to receive their second dose of the vaccine. the move “very unfair.” Anthony Fauci, America’s leading infectious disease expert, also weighed in on the UK’s decision in an on NBC’s Show on Thursday. The two-dose is “out” study, “he said, without specifying by whom.” I still think, if done right, you can do a single dose, reserve for the second dose and keep doing the job. ” said Fauci. But he added, “You can argue, and some people are, about expanding the and giving a single dose at all levels and hoping you will get the second dose on time.” to give it to the in dividus. In its statement, Pfizer said monitoring was needed on all alternative vaccination schedules and that authorities should work to ensure that each recipient receives the maximum protection possible. “Data from the Phase 3 study demonstrated that although partial protection against the vaccine appears to begin as early as 12 days after the first dose, two of the vaccine are needed to provide maximum protection against the disease, vaccine efficacy. by 95%, ”Pfizer said in its statement. An FDA document containing frequently asked about the vaccine from Pfizer and its partner BioNTech SE notes that the agency’s assessment of the safety and efficacy of the vaccine was based on data from patients with received two injections three weeks apart. Subscribe to our YouTube channel: Bloomberg Quicktake brings you live global news and original programming covering business, technology, politics and culture. Make sense of the stories that change your business and your world. To watch full coverage on Bloomberg Quicktake 24/7, visit or watch on Apple TV, Roku, Samsung Smart TV, Fire TV, and Android TV on the Bloomberg app. Got a story to tell? Fill out this survey for a chance to get it featured on Bloomberg Quicktake: Connect with us on… YouTube: Latest on YouTube: Twitter: Facebook: Instagram:
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